{"product_id":"casein-kinase-iiβ-s205-polyclonal-antibody-bs1529","title":"Casein Kinase IIβ (S205) Polyclonal Antibody-BS1529","description":"\u003cp\u003eCasein Kinase IIβ (S205) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS1529-50, BS1529-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P67870\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e \n\n\u003cp\u003eBackground: Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine\/threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIα, γ, ε and δ, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The α catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CK2-β (S205) polyclonal antibody detects endogenous levels of CK2-β protein.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Casein Kinase IIβ (S205) pAb at 1:500 dilution\u003cbr\u003e\nLane 1: HEK293 whole cell lysate (40ug)\u003cbr\u003e\nLane 2: A2780 whole cell lysate (40ug)\u003cbr\u003e\nLane 3: 3T3-L1 whole cell lysate (20ug), Immunohistochemistry (IHC) analyzes of Casein Kinase IIβ (S205) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.\u003c\/p\u003e \n\n\u003cp\u003eBioworld Molecular Weight: ~ 25 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Casein kinase II subunit beta; CK II beta; Phosvitin; Protein G5a; CSNK2B; CK2N; G5A; CKIIβ; CK2B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 175-220 of Human Casein Kinase IIβ.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42953212395699,"sku":"BS1529-50","price":254.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42953212428467,"sku":"BS1529-100","price":442.75,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_5ef629d5-7427-4b61-9a49-1dfa2b51b13e.jpg?v=1705056862","url":"https:\/\/afsbio.com\/products\/casein-kinase-ii%ce%b2-s205-polyclonal-antibody-bs1529","provider":"AFSBio Inc.","version":"1.0","type":"link"}