{"product_id":"casp9-monoclonal-antibody-bt-mca4045","title":"CASP9 Monoclonal Antibody - BT-MCA4045","description":"\u003cp\u003eCASP9 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4045-50, BT-MCA4045-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CASP9\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5E8C8\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CASP9\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CASP9 (AA: 331-416) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 46.3kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P55211\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 842\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238412148915,"sku":"BT-MCA4045-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238412181683,"sku":"BT-MCA4045-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f483e201-9ef1-4d08-ba06-ec2d3644c49d.png?v=1769380291","url":"https:\/\/afsbio.com\/products\/casp9-monoclonal-antibody-bt-mca4045","provider":"AFSBio Inc.","version":"1.0","type":"link"}