{"product_id":"caspase-2-polyclonal-antibody-e-ab-61085","title":"Caspase-2 Polyclonal Antibody - E-AB-61085","description":"\u003cp\u003eCaspase-2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-61085-60, E-AB-61085-120, E-AB-61085-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Caspase-2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CASP2; CASP-2; ICH1; NEDD-2; NEDD2; PPP1R57; caspase-2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Cell Biology,Metabolism\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P42575\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human Caspase-2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 10kDa\/34kDa\/50kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 48KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146147299507,"sku":"E-AB-61085-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146147365043,"sku":"E-AB-61085-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146147397811,"sku":"E-AB-61085-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_711c4825-e72d-45a0-a7d1-810af13511a3.png?v=1710291186","url":"https:\/\/afsbio.com\/products\/caspase-2-polyclonal-antibody-e-ab-61085","provider":"AFSBio Inc.","version":"1.0","type":"link"}