{"product_id":"caspase-3-4b8-mouse-mab-em1266","title":"Caspase-3 (4B8) Mouse mAb - EM1266","description":"\u003cp\u003eCaspase-3 (4B8) Mouse mAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: EM1266-50, EM1266-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP).\u003c\/p\u003e\n\n\u003cp\u003eAlternate Name: APOPAIN antibody, CASP 3 antibody, CPP32 antibody, Cysterine protease CPP32 antibody\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:100-200\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic Peptide\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG1\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 17, 32kDa\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 836\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P42574\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201993466035,"sku":"EM1266-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201993498803,"sku":"EM1266-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_48470fe0-93f1-47d7-a536-b4a842c173d4.png?v=1767119530","url":"https:\/\/afsbio.com\/products\/caspase-3-4b8-mouse-mab-em1266","provider":"AFSBio Inc.","version":"1.0","type":"link"}