{"product_id":"caspase-3-polyclonal-antibody-bs90187","title":"Caspase-3 Polyclonal Antibody-BS90187","description":"\u003cp\u003eCaspase-3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90187-50, BS90187-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P42574\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC IHC FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:500-1:1,000\u003cbr\u003e\nICC:1:200\u003cbr\u003e\nIHC:1:200\u003cbr\u003e\nFC:1:100-1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP). Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 17 kDa (p17) and a 12 kDa (p12) subunit.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Peptide affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Caspase-3 polyclonal antibody detects endogenous levels of Caspase-3 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 31 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Caspase-3 on different lysates using anti- Caspase-3 antibody at 1\/1,000 dilution. Positivecontrol: \u003cbr\u003e\n Lane 1: Human lung \u003cbr\u003e\n Lane 2: Human brain \u003cbr\u003e\n Lane 3: Jurkat \u003cbr\u003e\n Lane 4: F9 \u003cbr\u003e\n Lane 5: NCCTI \u003cbr\u003e\n Lane 6: Daudi \u003cbr\u003e\n Lane 7: Raji \u003cbr\u003e\n Lane 8: MCF-7 \u003cbr\u003e\n Lane 9: Hela, ICC staining of Caspase-3 in HepG2 cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100\/PBS.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CASP-3, CPP-32, SCA-1, A830040C14Rik, Apopain, CASP-3, CASP3, CASP3, Casp3a, Caspase 3, Caspase 3, apoptosis-related cysteine peptidase, Caspase 3, apoptosis-related cysteine protease, Caspase 3, apoptosis-related cysteine protease a, Caspase-3 subunit p12, CC3, CPP-32, CPP32, CPP32B, Cysteine protease CPP32, EC 3.4.22.56, LICE, mldy, OTTHUMP00000165052, OTTHUMP00000165053, OTTHUMP00000165054, PARP cleavage protease, Procaspase3, Protein Yama, SCA 1, SCA-1, SREBP cleavage activity 1, Yama,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthetic peptide (KLH-coupled) witihin human Caspase-3 N-terminal.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42979767550131,"sku":"BS90187-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42979767582899,"sku":"BS90187-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_db8aedc6-06ef-4f76-b60a-7f83317a8c35.jpg?v=1705749006","url":"https:\/\/afsbio.com\/products\/caspase-3-polyclonal-antibody-bs90187","provider":"AFSBio Inc.","version":"1.0","type":"link"}