{"product_id":"caspase-7-p20-d198-polyclonal-antibody-bs7007","title":"Caspase-7 p20 (D198) Polyclonal Antibody - BS7007","description":"\u003cp\u003eCaspase-7 p20 (D198) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS7007-50, BS7007-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, Ced-3\/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9 and caspase-10. Ced-3\/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellμlar longevity. Poly(ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Apoptosis related cysteine peptidase, Apoptosis Related Cysteine Protease, Apoptotic protease Mch-3, Apoptotic Protease MCH3, CASP 7, CASP-7, CASP7, Caspase-7 subunit p11, Caspase7, CMH 1, CMH-1, CMH1, ICE LAP3, ICE like Apoptotic Protease 3, ICE-LAP3, ICE-like apoptotic protease 3, MCH3,\u003c\/p\u003e \n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 180-230 of Human Caspase 7.\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Caspase-7 p20 (D198) polyclonal antibody detects endogenous levels of the large fragment of caspase-7 resμlting from cleavage at Asp198. The antibody does not cross-react with fμll length caspase-7 or with other caspases.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 20 kDa\u003c\/p\u003e\n\n\u003cp\u003ePathway: Regμlation of Apoptosis, Inhibition of Apoptosis,\u003c\/p\u003e \n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P55210\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45946378125491,"sku":"BS7007-50","price":274.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45946378158259,"sku":"BS7007-100","price":457.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/caspase-7-p20-d198-polyclonal-antibody-bs7007","provider":"AFSBio Inc.","version":"1.0","type":"link"}