{"product_id":"cast-polyclonal-antibody-e-ab-11022","title":"CAST Polyclonal Antibody - E-AB-11022","description":"\u003cp\u003eCAST Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-11022-60, E-AB-11022-120, E-AB-11022-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CAST\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: BS 17; Calpain inhibitor; Calpastatin; Cast; Heart type calpastatin; ICAL; MGC9402; Sperm BS 17 component; Sperm BS-17 component\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P20810\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain\/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.8 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human CAST\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:100-1:300\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 77kDa\u003c\/p\u003e\n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136121307315,"sku":"E-AB-11022-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136121340083,"sku":"E-AB-11022-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136121372851,"sku":"E-AB-11022-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e05ddb4a-aab0-4e73-afd0-0ac05929ad18.png?v=1709987898","url":"https:\/\/afsbio.com\/products\/cast-polyclonal-antibody-e-ab-11022","provider":"AFSBio Inc.","version":"1.0","type":"link"}