{"product_id":"catalase-phospho-tyr386-rabbit-pab-es7775","title":"Catalase (phospho Tyr386) rabbit pAb - ES7775","description":"\u003cp\u003eCatalase (phospho Tyr386) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES7775-50, ES7775-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: CAT; Catalase\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human Catalase around the phosphorylation site of Tyr385. AA range:361-410\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 59kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 847\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P04040\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Peroxisome.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202356601011,"sku":"ES7775-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202356633779,"sku":"ES7775-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_4ac1a663-e88c-4f0e-8e13-40b85192e21e.png?v=1767127363","url":"https:\/\/afsbio.com\/products\/catalase-phospho-tyr386-rabbit-pab-es7775","provider":"AFSBio Inc.","version":"1.0","type":"link"}