{"product_id":"catenin-α1-phospho-ser641-rabbit-pab-es4887","title":"Catenin-α1 (phospho Ser641) rabbit pAb - ES4887","description":"\u003cp\u003eCatenin-α1 (phospho Ser641) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES4887-50, ES4887-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: catenin alpha 1 (CTNNA1) Homo sapiens This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: CTNNA1; Catenin alpha-1; Alpha E-catenin; Cadherin-associated protein; Renal carcinoma antigen NY-REN-13\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000, Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human Catenin-alpha1 around the phosphorylation site of Ser641. AA range:607-656\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 1495\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P35221\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: [Isoform 1]: Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Found at cell-cell boundaries and probably at cell-matrix boundaries.; [Isoform 3]: Cell membrane; Peripheral membrane protein; Cytoplasmic side.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201810718899,"sku":"ES4887-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201810751667,"sku":"ES4887-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_3d899510-b447-404b-b68b-4ccfe78385db.png?v=1767112354","url":"https:\/\/afsbio.com\/products\/catenin-%ce%b11-phospho-ser641-rabbit-pab-es4887","provider":"AFSBio Inc.","version":"1.0","type":"link"}