{"product_id":"cathepsin-d-polyclonal-antibody-bt-ap01242","title":"Cathepsin D Polyclonal Antibody - BT-AP01242","description":"\u003cp\u003eCathepsin D Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01242-20, BT-AP01242-50, BT-AP01242-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CTSD encodes a member of the A1 family of peptidases. The encoded preproprotein (cathepsin D) is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CTSD\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cathepsin D Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 44552\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P07339; Mouse: P18242\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CTSD; CPSD; Cathepsin D\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1509\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240161566899,"sku":"BT-AP01242-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240161599667,"sku":"BT-AP01242-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240161632435,"sku":"BT-AP01242-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_26d8ceee-2c59-42ed-84ea-284cefb7fc88.png?v=1769404400","url":"https:\/\/afsbio.com\/products\/cathepsin-d-polyclonal-antibody-bt-ap01242","provider":"AFSBio Inc.","version":"1.0","type":"link"}