{"product_id":"cav1-3-rabbit-pab-es20797","title":"Cav1.3 rabbit pAb - ES20797","description":"\u003cp\u003eCav1.3 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES20797-50, ES20797-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: calcium voltage-gated channel subunit alpha1 D (CACNA1D) Homo sapiens Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2\/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2; Voltage-gated calcium channel subunit alpha Cav1.3)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC; IF\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:100-200\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic Peptide of Cav1.3 AA range: 1060-1140\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 245kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 776\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q01668\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Membrane; Multi-pass membrane protein.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202437013683,"sku":"ES20797-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202437046451,"sku":"ES20797-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_8e70ab6c-ec05-47d0-a1e0-6a342e75b5dd.png?v=1767129133","url":"https:\/\/afsbio.com\/products\/cav1-3-rabbit-pab-es20797","provider":"AFSBio Inc.","version":"1.0","type":"link"}