{"product_id":"cav1-polyclonal-antibody-e-ab-70344","title":"CAV1 Polyclonal Antibody - E-AB-70344","description":"\u003cp\u003eCAV1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-70344-60, E-AB-70344-120, E-AB-70344-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CAV1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: BSCL3; CAV; CAV1; CAV1; caveolae protein; 22 kD; caveolin 1 alpha isoform; caveolin 1 beta isoform; Caveolin 1 caveolae protein 22kDa; Caveolin-1; Caveolin1; cell growth-inhibiting protein 32; CGL3; LCCNS; MSTP085; OTTHUMP00000025031; PPH3; VIP 21; VIP21\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction, Tags and Cell Markers\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q03135,P49817,P41350\u003c\/p\u003e\n\n\u003cp\u003eBackground: Caveolin-1 (CAV1), a multifunctional protein, is the main constituent molecule of caveolae and represents a scaffolding molecule for several signaling molecules including epidermal growth factor receptor . Several studies have implicated that a reduced expression of CAV1 was found in cancers including head and neck carcinoma . However, other studies recognize CAV1 as a tumor promoter because CAV1 is overexpressed in various kinds of cancers, especially in oral cancer . Recent study also show that CAV1 is involved in astric Cancer .\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.9 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH conjugated Synthetic peptide corresponding to Mouse Caveolin-1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000,  IHC 1:500-1:1000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 20kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 20kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146520592563,"sku":"E-AB-70344-60","price":224.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146520625331,"sku":"E-AB-70344-120","price":364.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146520658099,"sku":"E-AB-70344-200","price":574.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_0e5040dd-138c-4abe-940e-aecbdf1dcb53.png?v=1710296808","url":"https:\/\/afsbio.com\/products\/cav1-polyclonal-antibody-e-ab-70344","provider":"AFSBio Inc.","version":"1.0","type":"link"}