{"product_id":"cav2-3-polyclonal-antibody-bs90203","title":"CaV2.3 Polyclonal Antibody-BS90203","description":"\u003cp\u003eCaV2.3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90203-50, BS90203-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q15878(Human) Q61290(Mouse) Q07652(Rat)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB\t1:500 - 1:2000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel. They are however insensitive to dihydropyridines (DHP). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Peptide affinity purified.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CaV2.3 polyclonal antibody detects endogenous levels of CaV2.3 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 262 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: ICC staining CaV2.3 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100\/PBS., Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-CaV2.3 antibody. Counter stained with hematoxylin.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: BII, CACNA1E, CACH6, CACNL1A6, alpha-1 polypeptide, BII, Brain calcium channel II, CAC 1E, CAC1E, CAC1E, CACH 6, CACH6, CACNA1E, Cacnl1 a6, CACNL1A6, Calcium channel, Calcium channel, L type, alpha 1 polypeptide, isoform 6, calcium channel, R type, Cav 2.3, Cchra 1, Cchra1, isoform 6, L type, Voltage dependent R type calcium channel subunit alpha 1E, Voltage gated calcium channel subunit alpha Cav2.3, Voltage-dependent R-type calcium channel subunit alpha-1E, Voltage-gated calcium channel subunit alpha Cav2.3,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthetic peptide within rat CaV2.3 aa 860-910.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42979768107187,"sku":"BS90203-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42979768139955,"sku":"BS90203-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_e8f9786f-6f06-4c94-9090-7c366ece3473.jpg?v=1705749024","url":"https:\/\/afsbio.com\/products\/cav2-3-polyclonal-antibody-bs90203","provider":"AFSBio Inc.","version":"1.0","type":"link"}