{"product_id":"cc14b-polyclonal-antibody-bt-ap14727","title":"CC14B Polyclonal Antibody - BT-AP14727","description":"\u003cp\u003eCC14B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14727-20, BT-AP14727-50, BT-AP14727-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CDC14B\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Dual specificity protein phosphatase CDC14B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O60729; Mouse: Q6PFY9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Dual specificity protein phosphatase CDC14B;EC 3.1.3.16;EC 3.1.3.48;CDC14 cell division cycle 14 homolog B\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8555\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239078158515,"sku":"BT-AP14727-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239078191283,"sku":"BT-AP14727-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239078224051,"sku":"BT-AP14727-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e3d8e83d-8829-4e9f-be6d-58d2d944006c.png?v=1769388816","url":"https:\/\/afsbio.com\/products\/cc14b-polyclonal-antibody-bt-ap14727","provider":"AFSBio Inc.","version":"1.0","type":"link"}