{"product_id":"ccdc106-polyclonal-antibody-e-ab-11038","title":"CCDC106 Polyclonal Antibody - E-AB-11038","description":"\u003cp\u003eCCDC106 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-11038-60, E-AB-11038-120, E-AB-11038-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CCDC106\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CC106; Ccdc106; Coiled-coil domain-containing protein 106; HSU79303; Protein predicted by clone 23882; ZNF581\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9BWC9\u003c\/p\u003e\n\n\u003cp\u003eBackground: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.3 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human CCDC106\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:100-1:300\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL","offer_id":43124067893427,"sku":"E-AB-11038-200","price":558.6,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43124067926195,"sku":"E-AB-11038-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"60μL","offer_id":43124067958963,"sku":"E-AB-11038-60","price":200.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_046286e9-6e68-49e9-afb9-747ce304b276.png?v=1709723330","url":"https:\/\/afsbio.com\/products\/ccdc106-polyclonal-antibody-e-ab-11038","provider":"AFSBio Inc.","version":"1.0","type":"link"}