{"product_id":"ccl11-polyclonal-antibody-bs70816","title":"CCL11 Polyclonal Antibody-BS70816","description":"\u003cp\u003eCCL11 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS70816-50, BS70816-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P51671\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB 1:500 - 1:2000\u003cbr\u003e\nIHC 1:50 - 1:200 \u003cbr\u003e\nIF 1:50 - 1:100\u003c\/p\u003e\n\n\u003cp\u003eBackground: Eotaxin (also designated eotaxin-1) is a member of the C-C or β family of chemokines which is characterized by a pair of adjacent cysteine residues. Eotaxin was first purified from the bronchoalveolar lavage fluid of guinea pigs challenged with an aerosol allergen, and serves as a potent chemoattractant for eosinophils. Eosinophilia is a prominent feature of several allergic conditions and is thought to be a central event in maladies such as bronchial asthma, dermatitis, conjunctivitis and possibly inflammatory bowel disease. The cognate eotaxin receptor has been identified. Originally described as mouse orphan receptor (MIP-1a receptor-like 2), CKR-3 has been shown to not only serve as the high affinity receptor for eotaxin, but also for RANTES and MCP-3. CKR-3 is expressed on the cell surface of primary eosinophils and does not bind to other members of the C-C or C-X-C family of chemokines. CKR-3 also serves as a co-receptor for a restricted subset of viruses.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CCL11 polyclonal antibody detects endogenous levels of CCL11 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 20 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of extracts of various cell lines, using CCL11 antibody., Immunohistochemistry of paraffin-embedded rat brain using CCL11 antibody at dilution of 1:100 (40x lens)., Immunohistochemistry of paraffin-embedded human stomach using CCL11 antibody at dilution of 1:100 (40x lens).\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: SCYA11; Eotaxin; C-C motif chemokine 11; Eosinophil chemotactic protein; Small-inducible cytokine A11\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human CCL11.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42997577416883,"sku":"BS70816-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42997577449651,"sku":"BS70816-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_17f17a0f-bb1c-48de-8104-31c07fb17c76.jpg?v=1706270628","url":"https:\/\/afsbio.com\/products\/ccl11-polyclonal-antibody-bs70816","provider":"AFSBio Inc.","version":"1.0","type":"link"}