{"product_id":"ccl27-polyclonal-antibody-e-ab-17773","title":"CCL27 Polyclonal Antibody - E-AB-17773","description":"\u003cp\u003eCCL27 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-17773-60, E-AB-17773-120, E-AB-17773-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CCL27\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ALP; C-C motif chemokine 27; CC chemokine ILC; Ccl27; CCL27; Chemokine (C-C motif) ligand 27; CTACK; CTAK; Cutaneous T cell attracting chemokine; Cutaneous T-cell-attracting chemokine; ESkine; IL 11 R alpha locus chemokine; IL-11 R-alpha-locus chemokine; ILC; PESKY; SCYA27; Skinkine; Small inducible cytokine A27; small inducible cytokine subfamily A (Cys-Cys); member 27; Small-inducible cytokine A27\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9Y4X3\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. CCL27 (C-C Motif Chemokine Ligand 27) is a Protein Coding gene. Diseases associated with CCL27 include Dermatitis and Atopic Dermatitis. Among its related pathways are Peptide ligand-binding receptors and PEDF Induced Signaling. GO annotations related to this gene include chemokine activity. An important paralog of this gene is CCL28.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.5 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human CCL27\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:300, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43130657341619,"sku":"E-AB-17773-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43130657374387,"sku":"E-AB-17773-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43130657407155,"sku":"E-AB-17773-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_97048fe1-5b9f-4426-b77b-806658156c50.png?v=1709810902","url":"https:\/\/afsbio.com\/products\/ccl27-polyclonal-antibody-e-ab-17773","provider":"AFSBio Inc.","version":"1.0","type":"link"}