{"product_id":"cd10-monoclonal-antibody-5b8-bt-mca0271","title":"CD10 Monoclonal Antibody (5B8) - BT-MCA0271","description":"\u003cp\u003eCD10 Monoclonal Antibody (5B8)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-MCA0271-20, BT-MCA0271-50, BT-MCA0271-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology; Cancer; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MME\u003c\/p\u003e\n\n\u003cp\u003eApplications: IF, ICC, IHC-p\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Mouse,Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Neprilysin\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 85514\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P08473; Mouse: Q61391; Rat: P07861\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MME; EPN; Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; CD10\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4311; Mouse: 17380; Rat: 24590\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240033149107,"sku":"BT-MCA0271-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240033181875,"sku":"BT-MCA0271-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240033214643,"sku":"BT-MCA0271-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2d90ff5a-77df-466e-9bf9-2e418490aef9.png?v=1769402433","url":"https:\/\/afsbio.com\/products\/cd10-monoclonal-antibody-5b8-bt-mca0271","provider":"AFSBio Inc.","version":"1.0","type":"link"}