{"product_id":"cd10-polyclonal-antibody-ra22902","title":"CD10 Polyclonal Antibody - RA22902","description":"CD10 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA22902-50, RA22902-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: membrane metalloendopeptidase (MME) Homo sapiens This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL) . This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. IHC-p: 1\/100-1\/300. ELISA: 1\/20000. Not yet tested in other applications.\n\nAlternative Names: MME; EPN; Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; CD10\n\nApplications: WB; IHC-p; IF (paraffin section) ; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 4311\n\nProtein MW (KDa): 85\n\nSWISS: P08473\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121175879859,"sku":"RA22902-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121175912627,"sku":"RA22902-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d41f4d83-3ae7-4d28-96d5-928e47879fa4.png?v=1773371699","url":"https:\/\/afsbio.com\/products\/cd10-polyclonal-antibody-ra22902","provider":"AFSBio Inc.","version":"1.0","type":"link"}