{"product_id":"cd10-rabbit-polyclonal-antibody-ra22904","title":"CD10 Rabbit Polyclonal Antibody - RA22904","description":"CD10 Rabbit Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA22904-50, RA22904-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: membrane metalloendopeptidase (MME) Homo sapiens This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL) . This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: IHC 1:100-200\n\nAlternative Names: MME; YM3682\n\nApplications: IHC-p; IF (paraffin section) \n\nSpecies Cross-Reactivity: Human; Rat; Mouse\n\nGeneID (Human): 4311\n\nProtein MW (KDa): 85\n\nSWISS: P08473\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121176273075,"sku":"RA22904-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121176305843,"sku":"RA22904-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9987fd27-b8a4-432f-ac44-835b3df2ea6b.png?v=1773371702","url":"https:\/\/afsbio.com\/products\/cd10-rabbit-polyclonal-antibody-ra22904","provider":"AFSBio Inc.","version":"1.0","type":"link"}