{"product_id":"cd105-monoclonal-antibody-bt-mca3999","title":"CD105 Monoclonal Antibody - BT-MCA3999","description":"\u003cp\u003eCD105 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3999-50, BT-MCA3999-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD105\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2B2H2\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD105\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CD105 (AA: extra 342-586) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 70.6kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P17813\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ENG, END, HHT1, ORW1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 2022\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238392324275,"sku":"BT-MCA3999-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238392357043,"sku":"BT-MCA3999-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_71714728-b8ff-4bec-b0d2-39ec98fa5df5.png?v=1769379829","url":"https:\/\/afsbio.com\/products\/cd105-monoclonal-antibody-bt-mca3999","provider":"AFSBio Inc.","version":"1.0","type":"link"}