{"product_id":"cd105-rabbit-pab-es17746","title":"CD105 rabbit pAb - ES17746","description":"\u003cp\u003eCD105 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES17746-50, ES17746-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Endoglin (CD antigen CD105)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC; IF; WB\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC-p 1:50-200, WB 1:500-2000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human CD105\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 72kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 2022\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P17813\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane; Single-pass type I membrane protein.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202422694067,"sku":"ES17746-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202422726835,"sku":"ES17746-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_284f0094-4877-45b8-809c-a99b10672356.png?v=1767128852","url":"https:\/\/afsbio.com\/products\/cd105-rabbit-pab-es17746","provider":"AFSBio Inc.","version":"1.0","type":"link"}