{"product_id":"cd112-nectin2-polyclonal-antibody-ncp0248p","title":"CD112\/NECTIN2 Polyclonal Antibody-NCP0248P","description":"\u003cp\u003eCD112\/NECTIN2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: NCP0248P-50, NCP0248P-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q92692\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:2000~1:5000\u003cbr\u003e\nIF  1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive .Probable cell adhesion protein .\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CD112\/NECTIN2  polyclonal antibody detects endogenous levels of CD112\/NECTIN2 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 60-70 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of CD112\/NECTIN2 polyclonal antibody at 1:2000 dilution\u003cbr\u003e\n Lane 1: CT-26 whole cell lysate (30ug)\u003cbr\u003e\n Lane 2: H1792 whole cell lysate (20ug)\u003cbr\u003e\n Lane 3: HEK293T whole cell lysate (20ug), Immunofluorescence analysis of HEK293T cells using CD112\/NECTIN2 pAb at dilution of 1:200.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Nectin-2; Herpes virus entry mediator B; Herpesvirus entry mediator B; HveB; Nectin cell adhesion molecule 2; Poliovirus receptor-related protein 2; CD112\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human CD112\/NECTIN2.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42989585563827,"sku":"NCP0248P-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42989585596595,"sku":"NCP0248P-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_5d3eafc5-88fa-457c-9acf-45b2e89b9157.jpg?v=1706095809","url":"https:\/\/afsbio.com\/products\/cd112-nectin2-polyclonal-antibody-ncp0248p","provider":"AFSBio Inc.","version":"1.0","type":"link"}