{"product_id":"cd118-monoclonal-antibody-bt-mca2190","title":"CD118 Monoclonal Antibody - BT-MCA2190","description":"\u003cp\u003eCD118 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2190-50, BT-MCA2190-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD118\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 8E9D3\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD118\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human PLA2G7 (AA: 22-441) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 123.7kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P42702\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: LIFR, SWS, SJS2, STWS, LIF-R\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3977\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238378332339,"sku":"BT-MCA2190-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238378365107,"sku":"BT-MCA2190-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_0480be67-444d-4551-8513-bba1908c789b.png?v=1769379505","url":"https:\/\/afsbio.com\/products\/cd118-monoclonal-antibody-bt-mca2190","provider":"AFSBio Inc.","version":"1.0","type":"link"}