{"product_id":"cd11a-lfa-1a-itgal-polyclonal-antibody-e-ab-93180","title":"CD11a\/LFA-1A\/ITGAL Polyclonal Antibody - E-AB-93180","description":"\u003cp\u003eCD11a\/LFA-1A\/ITGAL Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-93180-60, E-AB-93180-120, E-AB-93180-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD11a\/LFA-1A\/ITGAL\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CD11A; LFA-1; LFA1A; CD11a; ITGAL\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Immunology, Signal Transduction, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P20701\u003c\/p\u003e\n\n\u003cp\u003eBackground: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human CD11a\/LFA-1A\/CD11a\/LFA-1A\/ITGAL\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 119kDa\/128kDa\/134kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 180kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146683285683,"sku":"E-AB-93180-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146683318451,"sku":"E-AB-93180-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146683351219,"sku":"E-AB-93180-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_112052cc-d5f4-4b07-8db5-33c8f423e64e.png?v=1710300083","url":"https:\/\/afsbio.com\/products\/cd11a-lfa-1a-itgal-polyclonal-antibody-e-ab-93180","provider":"AFSBio Inc.","version":"1.0","type":"link"}