{"product_id":"cd11a-monoclonal-antibody-bt-mca4341","title":"CD11a Monoclonal Antibody - BT-MCA4341","description":"\u003cp\u003eCD11a Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4341-50, BT-MCA4341-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD11a\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5G7C5\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2a\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD11a\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CD11a (AA: extra 26-194) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 128.8kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P20701\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ITGAL, LFA-1, LFA1A\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3683\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238537355443,"sku":"BT-MCA4341-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238537388211,"sku":"BT-MCA4341-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_0982c7da-f89a-4ee6-9a1e-6d998d5b3856.png?v=1769382344","url":"https:\/\/afsbio.com\/products\/cd11a-monoclonal-antibody-bt-mca4341","provider":"AFSBio Inc.","version":"1.0","type":"link"}