{"product_id":"cd11b-polyclonal-antibody-e-ab-60354","title":"CD11B Polyclonal Antibody - E-AB-60354","description":"\u003cp\u003eCD11B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-60354-60, E-AB-60354-120, E-AB-60354-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD11B\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6; ITGAM; CD11b\/ITAM\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Neuroscience, Signal Transduction, Stem Cells, Tags and Cell Markers\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P11215\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human CD11B (NP_001139280.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IF 1:50-1:200\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136819462323,"sku":"E-AB-60354-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136819495091,"sku":"E-AB-60354-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136819527859,"sku":"E-AB-60354-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_6c70b985-3603-4319-91b0-3e6c0a04ce12.png?v=1709992226","url":"https:\/\/afsbio.com\/products\/cd11b-polyclonal-antibody-e-ab-60354","provider":"AFSBio Inc.","version":"1.0","type":"link"}