{"product_id":"cd121b-monoclonal-antibody-bt-mca3830","title":"CD121B Monoclonal Antibody - BT-MCA3830","description":"\u003cp\u003eCD121B Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3830-50, BT-MCA3830-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1\/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD121B\u003c\/p\u003e\n\n\u003cp\u003eApplications: ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5D7B1\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD121B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CD121B (AA: extra 14-343) expressed in HEK293-6e cells supernatant.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 45.4kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P27930\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: IL1R2, IL1RB, IL1R2c, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 7850\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238395764915,"sku":"BT-MCA3830-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238395797683,"sku":"BT-MCA3830-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_aec290fc-14f9-4827-ab28-517d38865b6a.png?v=1769379897","url":"https:\/\/afsbio.com\/products\/cd121b-monoclonal-antibody-bt-mca3830","provider":"AFSBio Inc.","version":"1.0","type":"link"}