{"product_id":"cd124-monoclonal-antibody-bt-mca3347","title":"CD124 Monoclonal Antibody - BT-MCA3347","description":"\u003cp\u003eCD124 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3347-50, BT-MCA3347-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD124\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 4B12B12\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD124\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CD124 (AA: 26-232) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 89.7kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P24394\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: IL4R, IL4RA, IL-4RA\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3566\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238406414515,"sku":"BT-MCA3347-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238406447283,"sku":"BT-MCA3347-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3709b4b6-0983-4a50-ac70-871cab2c79bb.png?v=1769380151","url":"https:\/\/afsbio.com\/products\/cd124-monoclonal-antibody-bt-mca3347","provider":"AFSBio Inc.","version":"1.0","type":"link"}