{"product_id":"cd135-polyclonal-antibody-bz16217","title":"CD135 Polyclonal Antibody - BZ16217","description":"\u003cp\u003eCD135 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16217-50, BZ16217-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a class III receptor tyrosine kinase that regμlates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellμlar domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates mμltiple cytoplasmic effector molecμles in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that resμlt in the constitutive activation of this receptor resμlt in acute myeloid leukemia and acute lymphoblastic leukemia.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: FLT3, CD135, FLK2, STK1, Receptor-type tyrosine-protein kinase FLT3, FL cytokine receptor, Fetal liver kinase-2, FLK-2, Fms-like tyrosine kinase 3, FLT-3, Stem cell tyrosine kinase 1, STK-1, CD antigen CD135\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human FLT3. AA range:451-500\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1\/500-1\/1000 ELISA: 1\/10000\u003c\/p\u003e\n\n\u003cp\u003ePurification: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Calcμlated MW: 113 kDa, Observed MW: 110 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P36888\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45940883718323,"sku":"BZ16217-50","price":349.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45940883751091,"sku":"BZ16217-100","price":582.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_d8474db2-20f3-4b2c-92df-0d7099582232.jpg?v=1788363543","url":"https:\/\/afsbio.com\/products\/cd135-polyclonal-antibody-bz16217","provider":"AFSBio Inc.","version":"1.0","type":"link"}