{"product_id":"cd137-monoclonal-antibody-bt-mca4140","title":"CD137 Monoclonal Antibody - BT-MCA4140","description":"\u003cp\u003eCD137 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4140-50, BT-MCA4140-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR\/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD137\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2A12C2\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD137\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CD137 (AA: 214-255) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 27.9kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q07011\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TNFRSF9, ILA, 4-1BB, CDw137\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3604\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238404513971,"sku":"BT-MCA4140-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238404546739,"sku":"BT-MCA4140-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9cd16150-a221-4159-a6cc-66cf6148f9b4.png?v=1769380113","url":"https:\/\/afsbio.com\/products\/cd137-monoclonal-antibody-bt-mca4140","provider":"AFSBio Inc.","version":"1.0","type":"link"}