{"product_id":"cd137l-polyclonal-antibody-bt-ap01353","title":"CD137L Polyclonal Antibody - BT-AP01353","description":"\u003cp\u003eCD137L Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01353-20, BT-AP01353-50, BT-AP01353-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein (tumor necrosis factor superfamily member 9) encoded by TNFSF9 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9\/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9\/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9\/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TNFSF9\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD137L Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 26625\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P41273; Mouse: P41274\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TNFSF9; Tumor necrosis factor ligand superfamily member 9; 4-1BB ligand; 4-1BBL\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8744\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240167039155,"sku":"BT-AP01353-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240167071923,"sku":"BT-AP01353-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240167104691,"sku":"BT-AP01353-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ac13869d-9c4e-47d0-8eb5-a606d7eb00a5.png?v=1769404488","url":"https:\/\/afsbio.com\/products\/cd137l-polyclonal-antibody-bt-ap01353","provider":"AFSBio Inc.","version":"1.0","type":"link"}