{"product_id":"cd14-polyclonal-antibody-ncp0176p","title":"CD14 Polyclonal Antibody-NCP0176P","description":"\u003cp\u003eCD14 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: NCP0176P-50, NCP0176P-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P08571\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:5000~1:10000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Coreceptor for bacterial lipopolysaccharide.In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96\/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS).Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response .\u003cbr\u003e\nActs as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway .Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL- .\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CD14 polyclonal antibody detects endogenous levels of CD14 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of CD14 polyclonal antibody at 1:5000 dilution\u003cbr\u003e\nLane1:MCF-7 cell membrane lysate(25ug)\u003cbr\u003e\nLane2:A549 cell membrane lysate(25ug)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~45 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD14; Monocyte differentiation antigen CD14, urinary form; Monocyte differentiation antigen CD14, membrane-bound form\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human CD14.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42908705423539,"sku":"NCP0176P-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42908705456307,"sku":"NCP0176P-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_1b736599-395c-4e68-b5d9-37a1d85abd50.jpg?v=1703006054","url":"https:\/\/afsbio.com\/products\/cd14-polyclonal-antibody-ncp0176p","provider":"AFSBio Inc.","version":"1.0","type":"link"}