{"product_id":"cd141-thrombomodulin-rabbit-polymab®-a22989pm","title":"CD141\/Thrombomodulin Rabbit PolymAb® - A22989PM","description":"\u003cp\u003eCD141\/Thrombomodulin Rabbit PolymAb®\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A22989PM-20, A22989PM-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, IF\/ICC, FC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 60kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 90kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment) .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 7056\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P07204\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: TM; THRM; AHUS6; BDCA3; CD141; BDCA-3; THPH12\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:2000 - 1:10000 IHC-P, 1:100 - 1:500 IF\/ICC, 1:50 - 1:200 FC, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology Inflammation, CDs, Stem Cells, Cardiovascular, Blood.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: THBD\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189840568499,"sku":"A22989PM-20","price":165.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189840601267,"sku":"A22989PM-100","price":431.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_bedb1bc7-a5d4-4a4e-af89-9cd5ae9f9316.png?v=1766436512","url":"https:\/\/afsbio.com\/products\/cd141-thrombomodulin-rabbit-polymab%c2%ae-a22989pm","provider":"AFSBio Inc.","version":"1.0","type":"link"}