{"product_id":"cd158a-polyclonal-antibody-ra22936","title":"CD158a Polyclonal Antibody - RA22936","description":"CD158a Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA22936-50, RA22936-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 (KIR2DL1) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC) . The gene content of the KIR gene cluster varies among haplotypes, although several \"framework\" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2) . The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\n\nAlternative Names: KIR2DL1; CD158A; NKAT1; Killer cell immunoglobulin-like receptor 2DL1; CD158 antigen-like family member A; MHC class I NK cell receptor; Natural killer-associated transcript 1; NKAT-1; p58 natural killer cell receptor clones CL-42\/47.11; p58 NK receptor CL-42\/47.11; p58.1 MHC class-I-specific NK receptor; CD158a\n\nApplications: WB; ELISA\n\nSpecies Cross-Reactivity: Human; Rat; Mouse\n\nGeneID (Human): 3802\n\nProtein MW (KDa): 39\n\nSWISS: P43626\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121177911475,"sku":"RA22936-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121177944243,"sku":"RA22936-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8bae87ae-8122-4cba-a8c4-eccc74b3df12.png?v=1773371739","url":"https:\/\/afsbio.com\/products\/cd158a-polyclonal-antibody-ra22936","provider":"AFSBio Inc.","version":"1.0","type":"link"}