{"product_id":"cd158e-polyclonal-antibody-ra22938","title":"CD158e Polyclonal Antibody - RA22938","description":"CD158e Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA22938-50, RA22938-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 (KIR3DL1) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC) . The gene content of the KIR gene cluster varies among haplotypes, although several \"framework\" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2) . The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. IHC-p: 1:100-1:300. ELISA: 1\/10000. Not yet tested in other applications.\n\nAlternative Names: KIR3DL1; CD158E; NKAT3; NKB1; Killer cell immunoglobulin-like receptor 3DL1; CD158 antigen-like family member E; HLA-BW4-specific inhibitory NK cell receptor; MHC class I NK cell receptor; Natural killer-associated transcript 3; NKAT-3; p70 natural killer cell receptor clones CL-2\/CL-11; p70 NK receptor CL-2\/CL-11; CD158e\n\nApplications: WB; IHC-p; IF (paraffin section) ; ELISA\n\nSpecies Cross-Reactivity: Human; Rat; Mouse\n\nGeneID (Human): 3811\n\nProtein MW (KDa): 50\n\nSWISS: P43629\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121178042547,"sku":"RA22938-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121178075315,"sku":"RA22938-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c2f07799-c9e6-4bcf-9c45-0796c760d84a.png?v=1773371742","url":"https:\/\/afsbio.com\/products\/cd158e-polyclonal-antibody-ra22938","provider":"AFSBio Inc.","version":"1.0","type":"link"}