{"product_id":"cd158k-polyclonal-antibody-ra22942","title":"CD158k Polyclonal Antibody - RA22942","description":"CD158k Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA22942-50, RA22942-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 (KIR3DL2) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC) . The gene content of the KIR gene cluster varies among haplotypes, although several \"framework\" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2) . The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: IHC-p 1:50-200, ELISA 1:10000-20000\n\nAlternative Names: Killer cell immunoglobulin-like receptor 3DL2 (CD158 antigen-like family member K;MHC class I NK cell receptor;Natural killer-associated transcript 4;NKAT-4;p70 natural killer cell receptor clone CL-5;p70 NK receptor CL-5;CD antigen CD158k) \n\nApplications: IHC-p; IF (paraffin section) ; ELISA\n\nSpecies Cross-Reactivity: Human; Rat; Mouse\n\nGeneID (Human): 3812\n\nSWISS: P43630\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45119734087859,"sku":"RA22942-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45119734120627,"sku":"RA22942-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8537195b-8bcf-4781-afe2-db346981b55d.png?v=1773356408","url":"https:\/\/afsbio.com\/products\/cd158k-polyclonal-antibody-ra22942","provider":"AFSBio Inc.","version":"1.0","type":"link"}