{"product_id":"cd16-monoclonal-antibody-q32-bt-mca0017","title":"CD16 Monoclonal Antibody (Q32) - BT-MCA0017","description":"\u003cp\u003eCD16 Monoclonal Antibody (Q32)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-MCA0017-20, BT-MCA0017-50, BT-MCA0017-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: FCGR3A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF,\u003c\/p\u003e \n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Low affinity immunoglobulin gamma Fc region receptor III-A\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 27940\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P08637; O75015\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: FCGR3A; FCGR3B\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2214; 2215\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240025809075,"sku":"BT-MCA0017-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240025841843,"sku":"BT-MCA0017-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240025874611,"sku":"BT-MCA0017-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_39cb1406-3318-4251-b74c-79fe230a08f2.png?v=1769402324","url":"https:\/\/afsbio.com\/products\/cd16-monoclonal-antibody-q32-bt-mca0017","provider":"AFSBio Inc.","version":"1.0","type":"link"}