{"product_id":"cd162-psgl-1-rabbit-polymab®-a26626pm","title":"CD162\/PSGL-1 Rabbit PolymAb® - A26626PM","description":"\u003cp\u003eCD162\/PSGL-1 Rabbit PolymAb®\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A26626PM-20, A26626PM-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\/ICC, IF-P, IHC-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 43kDa\/42kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 125kDa\/250kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment) .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\/Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 6404\/20345\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q14242\/Q3TA56\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CLA; CD162; PSGL1; PSGL-1; CD162\/PSGL-1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:50000 - 1:200000 IF\/ICC, 1:800 - 1:3200 IF-P, 1:800 - 1:3200 IHC-P, 1:1000 - 1:10000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Tumor immunology, Invasion and Metastasis, Cell Biology Developmental Biology, Apoptosis, Growth factors, Endocrine Metabolism, Immunology Inflammation, Cytokines, Interleukins, Cell Intrinsic Innate Immunity Signaling Pathway, Cardiovascular, Angiogenesis.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Selplg\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189882839219,"sku":"A26626PM-20","price":165.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189882871987,"sku":"A26626PM-100","price":431.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_856cc153-5f5b-4975-8cb2-65aa8a2ed74c.png?v=1766437395","url":"https:\/\/afsbio.com\/products\/cd162-psgl-1-rabbit-polymab%c2%ae-a26626pm","provider":"AFSBio Inc.","version":"1.0","type":"link"}