{"product_id":"cd167a-polyclonal-antibody-ncp0289p","title":"CD167a Polyclonal Antibody-NCP0289P","description":"\u003cp\u003eCD167a Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: NCP0289P-50, NCP0289P-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q08345\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:1000~1:2000\u003cbr\u003e\nIF  1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CD167a polyclonal antibody detects endogenous levels of CD167a protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 95 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of CD167a polyclonal antibody at 1:1000 dilution\u003cbr\u003e\n Lane 1: BV2 whole cell lysate (30ug)\u003cbr\u003e\n Lane 2: PC12 whole cell lysate (30ug)\u003cbr\u003e\n Lane 3: MCF-7 whole cell lysate (30ug)\u003cbr\u003e\n Lane 4: A375 whole cell lysate (30ug)\u003cbr\u003e\n Lane 5: HEK293T whole cell lysate (30ug), Immunofluorescence analysis of MCF-7 cells using CD167a pAb at dilution of 1:200.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Epithelial discoidin domain-containing receptor 1; Epithelial discoidin domain receptor 1; CD167 antigen-like family member A; Cell adhesion kinase; Discoidin receptor tyrosine kinase; HGK2; Mammary carcinoma kinase 10; MCK-10; Protein-tyrosine kinase 3A; Protein-tyrosine kinase RTK-6; TRK E; Tyrosine kinase DDR; Tyrosine-protein kinase CAK; DDR1; CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human CD167a.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42989588906163,"sku":"NCP0289P-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42989588938931,"sku":"NCP0289P-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_23d478c3-b09e-4d16-93f7-f0b1f5ee55f7.jpg?v=1706095826","url":"https:\/\/afsbio.com\/products\/cd167a-polyclonal-antibody-ncp0289p","provider":"AFSBio Inc.","version":"1.0","type":"link"}