{"product_id":"cd170-monoclonal-antibody-bt-mca4028","title":"CD170 Monoclonal Antibody - BT-MCA4028","description":"\u003cp\u003eCD170 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4028-50, BT-MCA4028-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD170\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3F5A3\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2a\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD170\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CD170 (AA: extra 17-230) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 60.7kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: O15389\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SIGLEC5, OBBP2, CD33L2, OB-BP2, SIGLEC-5\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 8778\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238529327283,"sku":"BT-MCA4028-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238529360051,"sku":"BT-MCA4028-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_325f308c-34a2-4f2d-b39d-4bd84fcf9fa3.png?v=1769382282","url":"https:\/\/afsbio.com\/products\/cd170-monoclonal-antibody-bt-mca4028","provider":"AFSBio Inc.","version":"1.0","type":"link"}