{"product_id":"cd177-monoclonal-antibody-bt-mca3380","title":"CD177 Monoclonal Antibody - BT-MCA3380","description":"\u003cp\u003eCD177 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3380-50, BT-MCA3380-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD177\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2F2C5\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD177\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CD177 (AA: extra 22-161) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 46.4kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q8N6Q3\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: NB1, PRV1, HNA2A, PRV-1, HNA-2a, NB1 GP\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 57126\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238528409779,"sku":"BT-MCA3380-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238528442547,"sku":"BT-MCA3380-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4b457841-89eb-4f60-a072-9bb46d6028b7.png?v=1769382277","url":"https:\/\/afsbio.com\/products\/cd177-monoclonal-antibody-bt-mca3380","provider":"AFSBio Inc.","version":"1.0","type":"link"}