{"product_id":"cd178-monoclonal-antibody-bt-mca3829","title":"CD178 Monoclonal Antibody - BT-MCA3829","description":"\u003cp\u003eCD178 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3829-50, BT-MCA3829-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS\/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD178\u003c\/p\u003e\n\n\u003cp\u003eApplications: ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2A6E12\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD178\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CD178 (AA: extra 103-281) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 31.5kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P48023\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: FASLG, APTL, FASL, CD95L, ALPS1B, CD95-L, TNFSF6, TNLG1A, APT1LG1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 356\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238386983091,"sku":"BT-MCA3829-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238387015859,"sku":"BT-MCA3829-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ab8be621-5542-46bb-a81e-11b66b77a5db.png?v=1769379713","url":"https:\/\/afsbio.com\/products\/cd178-monoclonal-antibody-bt-mca3829","provider":"AFSBio Inc.","version":"1.0","type":"link"}