{"product_id":"cd18-monoclonal-antibody-bt-mca2108","title":"CD18 Monoclonal Antibody - BT-MCA2108","description":"\u003cp\u003eCD18 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2108-50, BT-MCA2108-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD18\u003c\/p\u003e\n\n\u003cp\u003eApplications: ICC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 10E12\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD18\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of CD18 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 85kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P05107\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: LAD, MF17, LCAMB, LFA-1, ITGB2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3689\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238638149811,"sku":"BT-MCA2108-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238638182579,"sku":"BT-MCA2108-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_306a0f09-ada9-46b9-8fc5-48bcada94839.png?v=1769383304","url":"https:\/\/afsbio.com\/products\/cd18-monoclonal-antibody-bt-mca2108","provider":"AFSBio Inc.","version":"1.0","type":"link"}