{"product_id":"cd1b-polyclonal-antibody-e-ab-17775","title":"CD1B Polyclonal Antibody - E-AB-17775","description":"\u003cp\u003eCD1B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-17775-60, E-AB-17775-120, E-AB-17775-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD1B\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: A1 domain; CD1; CD1A; CD1b; CD1b antigen; CD1B antigen b polypeptide; CD1b molecule; CD1B; Cortical thymocyte antigen CD1A; Cortical thymocyte antigen CD1B; Differentiation antigen CD1 alpha 3; hTa1 thymocyte antigen; Ly38; Ly38; T cell surface glycoprotein CD1a; MGC125990; MGC125991; R1; T-cell surface glycoprotein CD1b; T6\/Leu6; Thymocite antigen CD1B\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P29016\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD1B (CD1b Molecule) is a Protein Coding gene. Diseases associated with CD1B include Mycobacterium Malmoense and Immune System Organ Benign Neoplasm. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Innate Immune System. GO annotations related to this gene include beta-2-microglobulin binding and endogenous lipid antigen binding. An important paralog of this gene is CD1C.This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.4 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human CD1B\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:300, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43130657570995,"sku":"E-AB-17775-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43130657603763,"sku":"E-AB-17775-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43130657636531,"sku":"E-AB-17775-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_737332fc-21cc-4077-8dfa-a8b60c5b908f.png?v=1709810907","url":"https:\/\/afsbio.com\/products\/cd1b-polyclonal-antibody-e-ab-17775","provider":"AFSBio Inc.","version":"1.0","type":"link"}