{"product_id":"cd1d-polyclonal-antibody-ncp0188p","title":"CD1D Polyclonal Antibody-NCP0188P","description":"\u003cp\u003eCD1D Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: NCP0188P-50, NCP0188P-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P15813\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:2000~1:5000\u003cbr\u003e\nIF  1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The CD1 multigene family encodes five forms of the CD1 T cell surface glyco_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x0002_protein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 mem_x005F_x0002_brane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 anti_x0002_gens are associated with b-2-Microglobulin and expressed on cortical thymo_x005F_x0002_cytes, Langerhans cells, a B cell subset and some dendritic cells. Adaptor pro_x0002_tein complexes and CD1-associated chaperones control CD1 trafficking and the development and activation of CD1-restricted T cells. CD1D is present on human intestinal epithelial cells (IEC) and exists as a b-2-Microglobulin_x0002_independent nonglycosylated form or a b-2-Microglobulin-dependent glycosy_x0002_lated form. The human CD1D gene maps to chromosome 1q23.1 and encodes a 335 amino acid protein that influences normal T cell maturation.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CD1D polyclonal antibody detects endogenous levels of CD1D protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 55 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of CD1D polyclonal antibody at 1:2000 dilution\u003cbr\u003e\n Lane 1: L02 cell membrane lysate (24ug)\u003cbr\u003e\n Lane 2: A549 cell membrane lysate (24ug), Immunofluorescence analysis of MCF-7 cells using CD1D pAb at dilution of 1:200.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Antigen-presenting glycoprotein CD1d; R3G1; CD1d; CD1D\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human CD1D.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42989584384179,"sku":"NCP0188P-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42989584416947,"sku":"NCP0188P-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_766e7608-8fd1-4f8c-b9d0-6d381b3a3a18.jpg?v=1706095776","url":"https:\/\/afsbio.com\/products\/cd1d-polyclonal-antibody-ncp0188p","provider":"AFSBio Inc.","version":"1.0","type":"link"}