{"product_id":"cd207-polyclonal-antibody-bt-ap01407","title":"CD207 Polyclonal Antibody - BT-AP01407","description":"\u003cp\u003eCD207 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01407-20, BT-AP01407-50, BT-AP01407-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: C-type lectin domain family 4 member K encoded by CD207 is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD207\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD207 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 36725\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9UJ71; Mouse: Q8VBX4\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CD207; CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 50489; Mouse: 246278\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240171724979,"sku":"BT-AP01407-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240171757747,"sku":"BT-AP01407-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240171790515,"sku":"BT-AP01407-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_28d8ee4e-ef7f-455b-8791-c700cff28e68.png?v=1769404547","url":"https:\/\/afsbio.com\/products\/cd207-polyclonal-antibody-bt-ap01407","provider":"AFSBio Inc.","version":"1.0","type":"link"}