{"product_id":"cd207-recombinant-protein-ncp0340","title":"CD207 Recombinant Protein - NCP0340","description":"\u003cp\u003eCD207 Recombinant Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 500μg, 1mg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: NCP0340-500, NCP0340-1000\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Langerin (CD207) is a C-type lectin receptor whose expression is restricted mainly to dendritic cells in the skin including Langerhans cells in the epidermis and langerin+\/CD103+ dermal dendritic cells. Langerin is found on the cell surface and within rod-shaped organelles called Birbeck granμles, and its expression is required for the formation of Birbeck granμles. Langerin recognizes carbohydrate motifs on the surface of pathogens, resμlting in endocytosis of the pathogen into Birbeck granμles, degradation of the pathogen, and antigen presentation to T cells.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Protein\u003c\/p\u003e \n\n\u003cp\u003eHost: E. coli\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is \u0026gt; 85% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~35kDa\u003c\/p\u003e\n\n\u003cp\u003eSolubility: PBS, 4M Urea, PH7.4\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eRestriction Sites: NdeI-XhoI\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q9UJ71\u003c\/p\u003e\n\n\u003cp\u003eTag: His-tag\u003c\/p\u003e\n\n\u003cp\u003eAmino Acid Sequence: PRFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFL\u003cbr\u003e\nKLKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKL\u003cbr\u003e\nLKRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYK\u003cbr\u003e\nTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSVRFWIPGEPNNAGNNEHCGNIKAPSLQ\u003cbr\u003e\nAWNDAPCDKTFLFICKRPYVPSEP\u003c\/p\u003e\n\n\u003cp\u003eExpression Vector: pet-22b(+)\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"500μg","offer_id":45979449196723,"sku":"NCP0340-500","price":1152.0,"currency_code":"CAD","in_stock":true},{"title":"1mg","offer_id":42887069106355,"sku":"NCP0340-1000","price":2052.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Protein_or_Antibody_Image.jpg?v=1788883694","url":"https:\/\/afsbio.com\/products\/cd207-recombinant-protein-ncp0340","provider":"AFSBio Inc.","version":"1.0","type":"link"}