{"product_id":"cd215-il-15r-alpha-polyclonal-antibody-e-ab-92503","title":"CD215\/IL-15R alpha Polyclonal Antibody - E-AB-92503","description":"\u003cp\u003eCD215\/IL-15R alpha Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-92503-60, E-AB-92503-120, E-AB-92503-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD215\/IL-15R alpha\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: IL15RA; CD215\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Metabolism, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q13261\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1\/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human CD215\/IL-15R alpha\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:1000, IF 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 15-28kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 60KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146639048883,"sku":"E-AB-92503-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146639081651,"sku":"E-AB-92503-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146639114419,"sku":"E-AB-92503-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_6fdfe9c3-3644-43b8-9975-f116f65e9c1b.png?v=1710299077","url":"https:\/\/afsbio.com\/products\/cd215-il-15r-alpha-polyclonal-antibody-e-ab-92503","provider":"AFSBio Inc.","version":"1.0","type":"link"}