{"product_id":"cd220-monoclonal-antibody-bt-mca4094","title":"CD220 Monoclonal Antibody - BT-MCA4094","description":"\u003cp\u003eCD220 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4094-50, BT-MCA4094-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD220\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1A1G3\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2a\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD220\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CD220 (AA: extra 413-624) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 156kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P06213\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: INSR, HHF5\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3643\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238379741363,"sku":"BT-MCA4094-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238379774131,"sku":"BT-MCA4094-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_bbe166bf-b09b-4548-a182-537714167f7f.png?v=1769379538","url":"https:\/\/afsbio.com\/products\/cd220-monoclonal-antibody-bt-mca4094","provider":"AFSBio Inc.","version":"1.0","type":"link"}